Natural Focus: How Saffron Improves Concentration for ADHD
Who would have thought that saffron, a culinary spice prominent in Asia, Europe, and the Middle East, could be an effective therapy for ADHD? showed the benefits of a therapeutic dose of saffron in children and adolescents with ADHD compared to a pharmaceutical stimulant. In fact, the dose of saffron performed just as well as the prescription medication methylphenidate.
The study also showed that saffron improved hyperactivity, sleep, and executive function. Both interventions were well tolerated. Most notably, saffron shortens the length of time to fall asleep, while many medications for ADHD cause insomnia or other sleep disturbances.
Saffron also has several bioactive compounds, including:
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- Crocin – a potent antioxidant that combats pro-inflammatory cytokines
- Crocetin – a compound with antioxidant, anti-inflammatory, and neuroprotective properties
- Safranal – acts as agonist of GABA receptors to promote a calming effect
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Unfortunately, ADHD is becoming more prevalent in children in America. New data shows that one in nine children in the U.S. are diagnosed with ADHD: “Findings published in the peer-reviewed Journal of Clinical Child & Adolescent Psychology uncover that approximately one million more children, aged 3–17, had received an ADHD diagnosis in 2022 than in 2016.” These staggering statistics show how much children today are struggling.
According to the 2022 National Survey of Children’s Health (NSCH ) dataset, “… among children currently living with ADHD:
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- 58% have moderate or severe ADHD
- 78% have at least one co-occurring disorder
- 54% received ADHD medication
- 44% had received behavioral treatment for ADHD in the past year.
- 30% did not receive any ADHD-specific treatment.”
At SFM, we utilize natural therapies to support children with hyperactivity, inattentiveness, and impulsivity. We also explore other contributing factors, such as toxins, nutritional deficiencies, and food sensitivities. Besides saffron, other natural therapies, including vitamins/minerals, fatty acids, anti-inflammatories, and nutrition interventions, are individualized for each patient. We also acknowledge the benefit of ample time for play, being in nature, and screen-free activities.
Before you run to your pantry to check your spices, talk to your medical provider about therapeutic dosing for your child based on weight and age.

Written by Laurel (Sunny) Austin, NP at Sanctuary Functional Medicine
References:
Bolhassani, Azam. Chapter 10 – Bioactive Components of Saffron and Their Pharmacological Properties, Editor(s): Atta-ur-Rahman, Studies in Natural Products Chemistry, Volume 58, 2018, Pages 289-311, ISSN 1572-5995, ISBN 9780444640567, https://doi.org/10.1016/B978-0-444-64056-7.00010-6. (https://www.sciencedirect.com/science/article/pii/B9780444640567000106)
Danielson, M. L., Claussen, A. H., Bitsko, R. H., Katz, S. M., Newsome, K., Blumberg, S. J., … Ghandour, R. (2024). ADHD Prevalence Among U.S. Children and Adolescents in 2022: Diagnosis, Severity, Co-Occurring Disorders, and Treatment. Journal of Clinical Child & Adolescent Psychology, 53(3), 343–360. https://doi.org/10.1080/15374416.2024.2335625
Taylor & Francis Group. “Approximately one in nine U.S. children diagnosed with ADHD, as new national study highlights an ‘ever-expanding’ public health concern.” ScienceDaily. ScienceDaily, 23 May 2024. <www.sciencedaily.com/releases/2024/05/240523112611.htm>.
Sanctuary Functional Medicine, under the direction of Dr Eric Potter, IFMCP MD, provides functional medicine services to Nashville, Middle Tennessee and beyond. We frequently treat patients from Kentucky, Alabama, Mississippi, Georgia, Ohio, Indiana, and more... offering the hope of healthier more abundant lives to those with chronic illness.