Our mothers may have taught us how to fold our clothes for easier placement in our dresser drawers, but proper folding appears to be important in the development of type I diabetes, an autoimmune disorder. Researchers have worked long and hard to understand how autoimmune diseases develop in search of prevention and treatment.
Everyone in genetics keeps hunting for the needles in the haystacks. Using data from almost 500 thousand healthy subject and over 230 thousand individuals with one of eight common psychiatric disorders, researchers found 109 genes linked to these mental health conditions. That was a lot of genes to wade through, but today’s computers allow us to do what in past decades was impossible.
Broccoli protects some kidneys better than others apparently. Recent research out of the American Society of Nephrology compared the effects of broccoli intake in those with and without the GSTM1 enzyme.
In 2 human cohorts and mice models the GSTM1 – glutathione S transferase M1 – enzyme correlated with increased kidney disease progression.
The study itself, while huge in science, has little immediate clinical utility. The implications of the study prove how dumb we are. Researchers at RIKEN Center for Integrative Medical Science and Istituto FIRC di Oncologia Molecolare (IFOM), along with collaborators from Kyoto University, the Karolinska Institut, and DNAFORM reported their use of NET-CAGE technology in finding 20,000 new genetic enhancer regions of DNA.
The vast advances in genetic testing ushered in a new era in which patients with illnesses are not the only ones to seek therapy guidance from genetic testing. Parents want to know what their children may face in the near and far term of life. Moving beyond the neonatal screening programs for cystic fibrosis,