Can Estradiol reduce visceral fat after Menopause?

Menopause, defined simply as the ceasing of menstruation, brings with it a plethora of changes to a woman’s body. Although there are a variety of reasons for a woman’s monthly cycle to stop, the most common one is menopause due to hormone loss, and specifically, estradiol, or estrogen loss. Although we are increasingly seeing women go through menopause at younger ages,

Cheer Up a Rat with Estrogen

If you have been following my blog for any length of time, you know that I appreciate the sacrifice that mice and rats make for science. In this case, researchers created heart attacks in rats and monitored them for depression with or without estrogen. They found that female rats who had their ovaries removed experienced more “rat depression” after this heart attack than female rats who were given an estrogen pellet after their ovaries were removed.

Hormone Cascade

Hormone Cascade

Where do hormones come from?  Do they just appear out of thin air?  Do they just ooze out of reproductive organs magically?  No, just like most of our body’s chemical messengers, they are made from other substances in us.  Our reproductive and adrenal hormones all begin as cholesterol, yes cholesterol.