What is MTHFR anyway?

Representing a classic Dr. Potter Blog:

Five Little Letters Can Spell Big Trouble

MTHFR = Methylenetetrahydrofolate Reductase.

For some reason, you now know that you have a mutation. School bullies may have claimed as much in years past, but now it is confirmed. Does it really matter if it is 677 or 1298 or whatever else the lab included for SHMT,

Essential Hypertension and MTHFR 677

MTHFR garners enough attention these days that the gene should run for office. Furthermore, it would have a great career in politics since it is accustomed to being blamed for everything medical under the sun anyway. This time Chinese researchers linked it to Essential Hypertension in a meta-analysis of other studies comparing the risk of high blood pressure in persons with the 677 or 1298 variation and those without the genetic change.

Chinese Prevent Strokes with Folate and Learn About MTHFR

Researchers in China recently released findings from a large study of 20,000 patients looking at whether folic acid (yes, the synthetic form) affected the stroke risk in those with high blood pressure. Several of the findings underscore the importance of the methylation cycle in cardiovascular health. Both individuals with MTHFR 677 mutations and those without should take notice of this study.

Asthma And Genetics: MTHFR Included

A recent study led by Carole Ober, PhD, Blum-Riese professor and chair of the Department of Human Genetics at the University of Chicago, found few clear links between gene mutations and asthma risk.  However, MTHFR was one of the three links that was discovered.  The International Business Times discusses the study HERE.

My comments are below:

Medical research is often both revealing and confusing.