EBV
Bibliography
Symptoms and Diseases associated with EBV:
Loebel, Madlen et al. “Deficient EBV-specific B- and T-cell response in patients with chronic fatigue syndrome” PloS one vol. 9,1 e85387. 15 Jan. 2014, doi:10.1371/journal.pone.0085387
Halpin, Peter et al. “Myalgic encephalomyelitis/chronic fatigue syndrome and gulf war illness patients exhibit increased humoral responses to the herpesviruses-encoded dUTPase: Implications in disease pathophysiology” Journal of medical virology vol. 89,9 (2017): 1636-1645.
The spread of EBV to ectopic lymphoid aggregates may be the final common pathway in the pathogenesis of ME/CFS. Eriksen W. Med Hypotheses. 2017 May;102:8-15. doi: 10.1016/j.mehy.2017.02.011. Epub 2017 Feb 28. PMID: 28478837
Valacyclovir treatment of chronic fatigue in adolescents. Henderson TA. Adv Mind Body Med. 2014 Winter;28(1):4-14. PMID: 24445302
Can persistent Epstein-Barr virus infection induce chronic fatigue syndrome as a Pavlov reflex of the immune response? Agliari E, Barra A, Vidal KG, Guerra F. J Biol Dyn. 2012;6:740-62. doi: 10.1080/17513758.2012.704083. PMID: 22873615
Hans Helmut Niller, Hans Wolf & Janos Minarovits (2008) Regulation and dysregulation of Epstein–Barr virus latency: Implications for the development of autoimmune diseases, Autoimmunity, 41:4, 298-328, DOI: 10.1080/08916930802024772
Epigenetic dysregulation of epstein-barr virus latency and development of autoimmune disease. Niller HH, Wolf H, Ay E, Minarovits J. Adv Exp Med Biol. 2011;711:82-102. Review. PMID: 21627044
Insoo Kang, Timothy Quan, Helena Nolasco, Sung-Hwan Park, Myung Sun Hong, Jill Crouch, Eric G. Pamer, John Greg Howe and Joe Craft. J Immunol January 15, 2004, 172 (2) 1287-1294; DOI: https://doi.org/10.4049/jimmunol.172.2.1287
EBV and systemic lupus erythematosus: a new perspective. Gross AJ, Hochberg D, Rand WM, Thorley-Lawson DA. J Immunol. 2005 Jun 1;174(11):6599-607. PMID: 15905498
Hooper, Philip L et al. “Loss of stress response as a consequence of viral infection: implications for disease and therapy” Cell stress & chaperones vol. 17,6 (2012): 647-55.
Eligio, Pizzigallo et al. “EBV Chronic Infections” Mediterranean journal of hematology and infectious diseases vol. 2,1 e2010022. 10 Aug. 2010, doi:10.4084/MJHID.2010.022
Michael P. Pender, “CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis,” Autoimmune Diseases, vol. 2012, Article ID 189096, 16 pages, 2012. https://doi.org/10.1155/2012/189096.
What is EBV?
Epstein-Barr Virus. Nowalk A, Green M. Microbiol Spectr. 2016 Jun;4(3). doi: 10.1128/microbiolspec.DMIH2-0011-2015. Review. PMID: 27337443
CDC website: https://www.cdc.gov/epstein-barr/about-mono.html
Mold link to EBV:
The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models. Accardi R, Gruffat H, Sirand C, Fusil F, Gheit T, Hernandez-Vargas H, Le Calvez-Kelm F, Traverse-Glehen A, Cosset FL, Manet E, Wild CP, Tommasino M. Carcinogenesis. 2015 Nov;36(11):1440-51. doi: 10.1093/carcin/bgv142. Epub 2015 Sep 30. PMID: 26424750
EBV Therapy:
Mikirova, Nina and Ronald Hunninghake. “Effect of high dose vitamin C on Epstein-Barr viral infection” Medical science monitor : international medical journal of experimental and clinical research vol. 20 725-32. 3 May. 2014, doi:10.12659/MSM.890423
Valacyclovir treatment in Epstein-Barr virus subset chronic fatigue syndrome: thirty-six months follow-up. Lerner AM, Beqaj SH, Deeter RG, Fitzgerald JT. In Vivo. 2007 Sep-Oct;21(5):707-13. PMID: 18019402
Valacyclovir: a review of its antiviral activity, pharmacokinetic properties, and clinical efficacy. Beutner KR. Antiviral Res. 1995 Dec;28(4):281-90. Review. PMID: 8669888
Pharmacokinetics and safety of valaciclovir in children with Epstein-Barr virus illness. Simon MW, Fish DN, Deeter RG. Drugs R D. 2002;3(6):365-73. PMID: 12516939
Andrei, G.; Trompet, E.; Snoeck, R. Novel Therapeutics for Epstein–Barr Virus. Molecules 2019, 24, 997.
Cohen, Jeffrey I. “Optimal treatment for chronic active Epstein-Barr virus disease” Pediatric transplantation vol. 13,4 (2009): 393-6.
Sanctuary Functional Medicine, under the direction of Dr Eric Potter, IFMCP MD, provides functional medicine services to Nashville, Middle Tennessee and beyond. We frequently treat patients from Kentucky, Alabama, Mississippi, Georgia, Ohio, Indiana, and more... offering the hope of healthier more abundant lives to those with chronic illness.
